Eli Lilly has announced that its Alzheimer’s treatment drug has slowed cognitive decline and functional decline in a study, giving millions of patients and their families “real hope that they will have a brighter future fighting this disease.”
The pharmaceutical company on Wednesday shared the results from its TRAILBLAZER-ALZ2 Phase 3 clinical trial of donanemab for the treatment of early symptomatic Alzheimer’s disease.
The drug significantly slowed cognitive and functional decline in patients. Trial participants who received the drug showed a significant reduction in amyloid plaque (a protein associated with Alzheimer’s), a slowing of cognitive decline by 35%, and slowing of functional decline by 40% over 18 months.
These are the “strongest phase 3 data for an Alzheimer’s treatment to date,” according to the Alzheimer’s Association chief science officer.
“This further underscores the inflection point we are at for the Alzheimer’s field,” added chief science officer Maria Carrillo. “The progress we’ve seen in this class of treatments, as well as the diversification of potential new therapies over the past few years, provides hope to those impacted by this devastating disease.”
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